Performance evaluation of BD FACSPresto™ point of care CD4 analyzer to enumerate CD4 counts for monitoring HIV infected individuals in Nigeria.
Identifieur interne : 000050 ( Main/Exploration ); précédent : 000049; suivant : 000051Performance evaluation of BD FACSPresto™ point of care CD4 analyzer to enumerate CD4 counts for monitoring HIV infected individuals in Nigeria.
Auteurs : Olubunmi Ruth Negedu-Momoh [Nigeria] ; Feyisayo Ebenezer Jegede [Nigeria] ; Ali Yakubu [Nigeria] ; Oluseyi Balogun [Nigeria] ; Musa Abdullahi [Nigeria] ; Titilope Badru [Nigeria] ; Edward Adekola Oladele [Nigeria] ; Chinedu Agbakwuru [Nigeria] ; Hadiza Khamofu [Nigeria] ; Kwasi Torpey [Nigeria]Source :
- PloS one [ 1932-6203 ] ; 2017.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Infections à VIH (immunologie), Infections à VIH (sang), Jeune adulte, Lymphocytes T CD4+ (immunologie), Lymphocytes T CD4+ (physiologie), Mâle, Nigeria, Numération des lymphocytes CD4 (), Pays en voie de développement, Population rurale, Prélèvement sanguin (), Reproductibilité des résultats, Sensibilité et spécificité, Sujet âgé, Systèmes automatisés lit malade.
- MESH :
- immunologie : Infections à VIH, Lymphocytes T CD4+.
- physiologie : Lymphocytes T CD4+.
- sang : Infections à VIH.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Mâle, Nigeria, Numération des lymphocytes CD4, Pays en voie de développement, Population rurale, Prélèvement sanguin, Reproductibilité des résultats, Sensibilité et spécificité, Sujet âgé, Systèmes automatisés lit malade.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Blood Specimen Collection (methods), CD4 Lymphocyte Count (methods), CD4-Positive T-Lymphocytes (immunology), CD4-Positive T-Lymphocytes (physiology), Developing Countries, Female, HIV Infections (blood), HIV Infections (immunology), Humans, Male, Middle Aged, Nigeria, Point-of-Care Systems, Reproducibility of Results, Rural Population, Sensitivity and Specificity, Young Adult.
- MESH :
- blood : HIV Infections.
- immunology : CD4-Positive T-Lymphocytes, HIV Infections.
- methods : Blood Specimen Collection, CD4 Lymphocyte Count.
- physiology : CD4-Positive T-Lymphocytes.
- Adolescent, Adult, Aged, Developing Countries, Female, Humans, Male, Middle Aged, Nigeria, Point-of-Care Systems, Reproducibility of Results, Rural Population, Sensitivity and Specificity, Young Adult.
Abstract
Despite the upsurge in support and intervention of donor agencies in HIV care and treatment programing in Sub-Sahara African, antiretroviral (ART) programs are still confronted with access and coverage challenges which influence enrolment of new patients. This study investigated the validity of point of care BD FACSPresto™ CD4 analyzer for CD4+ cell count, overall agreement, correlation, sensitivity, and specificity in comparison to a reference standard flow cytometry method. We also assessed the feasibility of use among non-laboratorians.
DOI: 10.1371/journal.pone.0178037
PubMed: 28542359
Affiliations:
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Le document en format XML
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monitoring HIV infected individuals in Nigeria.</title><author><name sortKey="Negedu Momoh, Olubunmi Ruth" sort="Negedu Momoh, Olubunmi Ruth" uniqKey="Negedu Momoh O" first="Olubunmi Ruth" last="Negedu-Momoh">Olubunmi Ruth Negedu-Momoh</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Jegede, Feyisayo Ebenezer" sort="Jegede, Feyisayo Ebenezer" uniqKey="Jegede F" first="Feyisayo Ebenezer" last="Jegede">Feyisayo Ebenezer Jegede</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Yakubu, Ali" sort="Yakubu, Ali" uniqKey="Yakubu A" first="Ali" last="Yakubu">Ali Yakubu</name><affiliation wicri:level="1"><nlm:affiliation>Murtala Mohammed Specialist Hospital, Kano, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Murtala Mohammed Specialist Hospital, Kano</wicri:regionArea><wicri:noRegion>Kano</wicri:noRegion></affiliation></author><author><name sortKey="Balogun, Oluseyi" sort="Balogun, Oluseyi" uniqKey="Balogun O" first="Oluseyi" last="Balogun">Oluseyi Balogun</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Abdullahi, Musa" 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Oladele</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Agbakwuru, Chinedu" sort="Agbakwuru, Chinedu" uniqKey="Agbakwuru C" first="Chinedu" last="Agbakwuru">Chinedu Agbakwuru</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Khamofu, Hadiza" sort="Khamofu, Hadiza" uniqKey="Khamofu H" first="Hadiza" last="Khamofu">Hadiza Khamofu</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author><author><name sortKey="Torpey, Kwasi" sort="Torpey, Kwasi" uniqKey="Torpey K" first="Kwasi" last="Torpey">Kwasi Torpey</name><affiliation wicri:level="1"><nlm:affiliation>Family Health International (FHI360), Garki- Abuja, Nigeria.</nlm:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Family Health International (FHI360), Garki- Abuja</wicri:regionArea><wicri:noRegion>Garki- Abuja</wicri:noRegion></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Blood Specimen Collection (methods)</term><term>CD4 Lymphocyte Count (methods)</term><term>CD4-Positive T-Lymphocytes (immunology)</term><term>CD4-Positive T-Lymphocytes (physiology)</term><term>Developing Countries</term><term>Female</term><term>HIV Infections (blood)</term><term>HIV Infections (immunology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nigeria</term><term>Point-of-Care Systems</term><term>Reproducibility of Results</term><term>Rural Population</term><term>Sensitivity and Specificity</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Infections à VIH (immunologie)</term><term>Infections à VIH (sang)</term><term>Jeune adulte</term><term>Lymphocytes T CD4+ (immunologie)</term><term>Lymphocytes T CD4+ (physiologie)</term><term>Mâle</term><term>Nigeria</term><term>Numération des lymphocytes CD4 ()</term><term>Pays en voie de développement</term><term>Population rurale</term><term>Prélèvement sanguin ()</term><term>Reproductibilité des résultats</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Systèmes automatisés lit malade</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à VIH</term><term>Lymphocytes T CD4+</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Blood Specimen Collection</term><term>CD4 Lymphocyte Count</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Lymphocytes T CD4+</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Developing Countries</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Nigeria</term><term>Point-of-Care Systems</term><term>Reproducibility of Results</term><term>Rural Population</term><term>Sensitivity and Specificity</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Nigeria</term><term>Numération des lymphocytes CD4</term><term>Pays en voie de développement</term><term>Population rurale</term><term>Prélèvement sanguin</term><term>Reproductibilité des résultats</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Systèmes automatisés lit malade</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite the upsurge in support and intervention of donor agencies in HIV care and treatment programing in Sub-Sahara African, antiretroviral (ART) programs are still confronted with access and coverage challenges which influence enrolment of new patients. This study investigated the validity of point of care BD FACSPresto™ CD4 analyzer for CD4+ cell count, overall agreement, correlation, sensitivity, and specificity in comparison to a reference standard flow cytometry method. We also assessed the feasibility of use among non-laboratorians.</div></front></TEI><affiliations><list><country><li>Nigeria</li></country></list><tree><country name="Nigeria"><noRegion><name sortKey="Negedu Momoh, Olubunmi Ruth" sort="Negedu Momoh, Olubunmi Ruth" uniqKey="Negedu Momoh O" first="Olubunmi Ruth" last="Negedu-Momoh">Olubunmi Ruth Negedu-Momoh</name></noRegion><name sortKey="Abdullahi, Musa" sort="Abdullahi, Musa" uniqKey="Abdullahi M" first="Musa" last="Abdullahi">Musa Abdullahi</name><name sortKey="Agbakwuru, Chinedu" sort="Agbakwuru, Chinedu" uniqKey="Agbakwuru C" first="Chinedu" last="Agbakwuru">Chinedu Agbakwuru</name><name sortKey="Badru, Titilope" sort="Badru, Titilope" uniqKey="Badru T" first="Titilope" last="Badru">Titilope Badru</name><name sortKey="Balogun, Oluseyi" sort="Balogun, Oluseyi" uniqKey="Balogun O" first="Oluseyi" last="Balogun">Oluseyi Balogun</name><name sortKey="Jegede, Feyisayo Ebenezer" sort="Jegede, Feyisayo Ebenezer" uniqKey="Jegede F" first="Feyisayo Ebenezer" last="Jegede">Feyisayo Ebenezer Jegede</name><name sortKey="Khamofu, Hadiza" sort="Khamofu, Hadiza" uniqKey="Khamofu H" first="Hadiza" last="Khamofu">Hadiza Khamofu</name><name sortKey="Oladele, Edward Adekola" sort="Oladele, Edward Adekola" uniqKey="Oladele E" first="Edward Adekola" last="Oladele">Edward Adekola Oladele</name><name sortKey="Torpey, Kwasi" sort="Torpey, Kwasi" uniqKey="Torpey K" first="Kwasi" last="Torpey">Kwasi Torpey</name><name sortKey="Yakubu, Ali" sort="Yakubu, Ali" uniqKey="Yakubu A" first="Ali" last="Yakubu">Ali Yakubu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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